%0 Journal Article %T Diversity of bat astroviruses in Lao PDR and Cambodia %+ Unité de Virologie / Virology Unit [Phnom Penh] %+ Ministry of Agriculture, Forestry and Fisheries [Cambodia] %+ Wildlife Conservation Society [Phnom Penh, Cambodia] %+ Institut de Systématique, Evolution, Biodiversité (ISYEB ) %+ Ministry of Agriculture and Forestry of Laos %+ Wildlife Conservation Society [Vientiane, Laos] (WCS) %+ Metabiota Inc. [Vientiane, Laos] %+ University of Warsaw (UW) %+ Wildlife Conservation Society (WCS) %+ University of California [Davis] (UC Davis) %+ Metabiota Inc. [Nanaimo, British Columbia, Canada] %+ Institut Pasteur du Cambodge %+ Interactions hôtes-vecteurs-parasites-environnement dans les maladies tropicales négligées dues aux trypanosomatides (UMR INTERTRYP) %+ Département Systèmes Biologiques (Cirad-BIOS) %+ GlaxoSmithKline Vaccines [Singapore] %A Lacroix, Audrey %A Duong, Veasna %A Hul, Vibol %A San, Sorn %A Davun, Holl %A Omaliss, Keo %A Chea, Sokha %A Hassanin, Alexandre %A Theppangna, Watthana %A Silithammavong, Soubanh %A Khammavong, Kongsy %A Singhalath, Sinpakone %A Afelt, Aneta %A Greatorex, Zoe %A Fine, Amanda, E. %A Goldstein, Tracey %A Olson, Sarah %A Joly, Damien, O. %A Keatts, Lucy %A Dussart, Philippe %A Frutos, Roger %A Buchy, Philippe %Z This study was made possible by the generous support of the American people through the United States Agency for International Development (USAID) Emerging Pandemic Threats PREDICT project (cooperative agreement number GHN-A-OO-09-00010-00). %< avec comité de lecture %@ 1567-1348 %J Infection, Genetics and Evolution %I Elsevier %V 47 %P 41 - 50 %8 2016-11-15 %D 2016 %R 10.1016/j.meegid.2016.11.013 %M 27871796 %K Astroviruses %K Bats %K Cambodia %K Genetic diversity %K Lao PDR %Z Life Sciences [q-bio]/Microbiology and Parasitology/VirologyJournal articles %X Astroviruses are known to infect humans and a wide range of animal species, and can cause gastroenteritis in their hosts. Recent studies have reported astroviruses in bats in Europe and in several locations in China. We sampled 1876 bats from 17 genera at 45 sites from 14 and 13 provinces in Cambodia and Lao PDR respectively, and tested them for astroviruses. Our study revealed a high diversity of astroviruses among various Yangochiroptera and Yinpterochiroptera bats. Evidence for varying degrees of host restriction for astroviruses in bats was found. Furthermore, additional Pteropodid hosts were detected. The astroviruses formed distinct phylogenetic clusters within the genus Mamastrovirus, most closely related to other known bat astroviruses. The astrovirus sequences were found to be highly saturated indicating that phylogenetic relationships should be interpreted carefully. An astrovirus clustering in a group with other viruses from diverse hosts, including from ungulates and porcupines, was found in a Rousettus bat. These findings suggest that diverse astroviruses can be found in many species of mammals, including bats. %G English %L pasteur-03214736 %U https://riip.hal.science/pasteur-03214736 %~ CIRAD %~ MNHN %~ RIIP %~ UPMC %~ EPHE %~ CNRS %~ UNIV-LYON1 %~ RIIP_CAMBODGE %~ ISYEB %~ AGROPOLIS %~ PSL %~ AGREENIUM %~ UPMC_POLE_3 %~ SORBONNE-UNIVERSITE %~ SU-SCIENCES %~ TEST-DEV %~ UDL %~ UNIV-LYON %~ EPHE-PSL %~ SU-TI %~ ALLIANCE-SU