%0 Journal Article %T Aerosol exposure of live bird market workers to viable influenza A/ H5N1 and A/ H9N2 viruses, Cambodia %+ Institut Pasteur du Cambodge %+ James Cook University (JCU) %+ Federation University [Churchill, Australia] %+ Ministry of Agriculture, Forestry and Fisheries [Cambodia] %A Horwood, Paul %A Horm, Srey Viseth %A Yann, Sokhoun %A Tok, Songha %A Chan, Malen %A Suttie, Annika %A Y, Phalla %A Rith, Sareth %A Siegers, Jurre %A San, Sorn %A Davun, Holl %A Tum, Sothyra %A Ly, Sowath %A Tarantola, Arnaud %A Dussart, Philippe %A Karlsson, Erik %Z This study was funded by the US Department of Health and Human Services, Office of the Assistant Secretary for Preparedness and Response (grant No. IDSEP 140020-01-00). E.A.K and further work at Institut Pasteur du Cambodge is supported, in part, by federal funds from the Food and Agriculture Organization of the United Nations, the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services Contract No. 1U01AI151758-01. Open access publishing facilitated by James Cook University, as part of the Wiley - James Cook University agreement via the Council of Australian University Librarians. %< avec comité de lecture %@ 1863-1959 %J Zoonoses and Public Health %I Wiley %V 70 %N 2 %P 171-175 %8 2023-03 %D 2023 %R 10.1111/zph.13009 %M 36409285 %K A/H5N1 %K A/H9N2 %K aerosol %K avian %K influenza %K live bird market %Z Life Sciences [q-bio]Journal articles %X Live bird markets (LBMs) have been identified as key factors in the spread, persistence and evolution of avian influenza viruses (AIVs). In addition, these settings have been associated with human infections with AIVs of pandemic concern. Exposure to aerosolised AIVs by workers in a Cambodian LBM was assessed using aerosol impact samplers. LBM vendors were asked to wear an air sampler for 30 min per day for 1 week while continuing their usual activities in the LBM during a period of high AIV circulation (February) and a period of low circulation (May). During the period of high circulation, AIV RNA was detected from 100% of the air samplers using molecular methods and viable AIV (A/H5N1 and/or A/H9N2) was isolated from 50% of air samplers following inoculation into embryonated chicken eggs. In contrast, AIV was not detected by molecular methods or successfully isolated during the period of low circulation. This study demonstrates the increased risk of aerosol exposure of LBM workers to AIVs during periods of high circulation and highlights the need for interventions during these high-risk periods. Novel approaches, such as environmental sampling, should be further explored at key high-risk interfaces as a potentially cost-effective alternative for monitoring pandemic threats. %G English %2 https://riip.hal.science/pasteur-04096779/document %2 https://riip.hal.science/pasteur-04096779/file/Zoonoses%20and%20Public%20Health%20-%202022%20-%20Horwood%20-%20Aerosol%20exposure%20of%20live%20bird%20market%20workers%20to%20viable%20influenza%20A%20H5N1%20and%20A.pdf %L pasteur-04096779 %U https://riip.hal.science/pasteur-04096779 %~ RIIP %~ RIIP_CAMBODGE %~ TEST3-HALCNRS