Therapeutic and Transmission-Blocking Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia - RIIP - Réseau International des Instituts Pasteur
Article Dans Une Revue Emerging Infectious Diseases Année : 2018

Therapeutic and Transmission-Blocking Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia

Résumé

We assessed the efficacy of standard 3-day courses of chloroquine and dihydroartemisinin/piperaquine against Plasmodium vivax malaria. Compared with chloroquine, dihydroartemisinin/piperaquine was faster in clearing asexual P. vivax parasites and blocking human-to-mosquito transmission. This drug combination was also more effective in preventing potential recurrences for >2 months.
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hal-02558722 , version 1 (30-04-2020)

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Jean Popovici, Amélie Vantaux, Lyse Primault, Reingsey Samreth, Eak Por Piv, et al.. Therapeutic and Transmission-Blocking Efficacy of Dihydroartemisinin/Piperaquine and Chloroquine against Plasmodium vivax Malaria, Cambodia. Emerging Infectious Diseases, 2018, 24 (8), pp.1516-1519. ⟨10.3201/eid2408.170768⟩. ⟨hal-02558722⟩
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