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Journal Articles Emerging Infectious Diseases Year : 2009

Multidrug-resistant Mycobacterium tuberculosis strain from Equatorial Guinea detected in Spain.

Maria J Iglesias
  • Function : Author
Maria S Jiménez
  • Function : Author
Laura Herrera-Leon
  • Function : Author
Elena Rodríguez-Valín
  • Function : Author
Nalin Rastogi
Josefa March
  • Function : Author
Rosa González-Palacios
  • Function : Author
Elia Palenque
  • Function : Author
Rafael Ayarza
  • Function : Author
Elena Hurra
  • Function : Author
Isolina Campos-Herrero
  • Function : Author
María A Vitoria
  • Function : Author
María A Lezcano
  • Function : Author
María J Revillo
  • Function : Author
Carlos Martin

Abstract

This investigation focused on a specific Multidrug-Resistant (MDR) Mycobacterium tuberculosis strain from Equatorial Guinea that had been imported into Spain. Ten MDR isolates from as many patients from Equatorial Guinea were detected in Spain during 2000 through 2008. All the 10 isolates exhibited an identical genotypic pattern belonging to the Latin-American and Mediterranean (LAM) genotypic lineage of M. tuberculosis designated SIT177-LAM 9. Evidence of clonality was found for all the 10 isolates by different molecular epidemiology methods and mutations involved in drug resistance. The analysis of the RDRio deletion confirmed that the strain belonged to the major RDRio sublineage of the Latin-American and Mediterranean (LAM) genotypic lineage of M. tuberculosis which has disseminated globally.
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Dates and versions

pasteur-00511967 , version 1 (26-08-2010)

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Patricia Gavín, Maria J Iglesias, Maria S Jiménez, Laura Herrera-Leon, Elena Rodríguez-Valín, et al.. Multidrug-resistant Mycobacterium tuberculosis strain from Equatorial Guinea detected in Spain.. Emerging Infectious Diseases, 2009, 15 (11), pp.1858-1860. ⟨10.3201/eid1511.090449⟩. ⟨pasteur-00511967⟩
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