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Journal Articles Trends in Parasitology Year : 2003

Class and subclass selection in parasite-specific antibody responses.

Abstract

Antibodies are characteristically induced in many parasitic infection processes. The class and subclass of the antibody response is instrumental because each isotype has a distinct biological function. It is thus crucially important for an infected individual to mount the most appropriate secondary antibody response--that is the response that has the best chance of clearing the infection and/or controlling disease. This represents a fundamental of vaccine strategies. Immuno-epidemiological surveys and in vitro models of antibody production have helped to understand some of the goals which should be achieved when designing antiparasitic vaccines.

Dates and versions

pasteur-00566839 , version 1 (17-02-2011)

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Olivier Garraud, Ronald Perraut, Gilles Riveau, Thomas B Nutman. Class and subclass selection in parasite-specific antibody responses.. Trends in Parasitology, 2003, 19 (7), pp.300-4. ⟨10.1016/S1471-4922(03)00139-9⟩. ⟨pasteur-00566839⟩
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