HB S [beta 6(A3)GLU -> VAL, GAG > GTG] AND beta-GLOBIN GENE CLUSTER HAPLOTYPE DISTRIBUTION IN MAURITANIA - RIIP - Réseau International des Instituts Pasteur Access content directly
Journal Articles Hemoglobin Year : 2012

HB S [beta 6(A3)GLU -> VAL, GAG > GTG] AND beta-GLOBIN GENE CLUSTER HAPLOTYPE DISTRIBUTION IN MAURITANIA

Abstract

Of 1050 Mauritanian blood donors screened from the two main racial groups, i.e., the Moors and Black Africans, 60 were found to carry Hb S [beta 6(A3) Glu -> Val, GAG>GTG], giving a global frequency of 5.71%. The prevalence observed in the Black African Mauritanians (10.69%) is almost five times that found in the Moor group (2.25%). Four of the five main beta(S) haplotypes were detected in this study: Senegal (77.8%), Benin (8.8%), Arab-Indian (5.5%) and Bantu (4.4%). These data showed that Hb S is a serious public health problem in Mauritania. They also confirm the ethnic heterogeneity of the Mauritanian population.
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pasteur-01375140 , version 1 (04-09-2017)

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Fatimetou M. Veten, Isselmou O. Abdelhamid, Ghlana M. Meiloud, Sidi M. Ghaber, Mohamed L. Salem, et al.. HB S [beta 6(A3)GLU -> VAL, GAG > GTG] AND beta-GLOBIN GENE CLUSTER HAPLOTYPE DISTRIBUTION IN MAURITANIA. Hemoglobin, 2012, 36 (4), pp.311-315. ⟨10.3109/03630269.2012.688782⟩. ⟨pasteur-01375140⟩

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