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Journal Articles Nature Biomedical Engineering Year : 2019

Tumour suppression by blocking palmitoylation

Stephane Lefrancois
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Abstract

Enhanced lysosomal degradation of the transmembrane protein programmed cell-death protein-1 ligand in tumour cells, enabled by blocking the protein’s post-translational lipid modification, promotes T-cell-mediated suppression of tumour growth in mice.

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Cancer
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Dates and versions

pasteur-02133023 , version 1 (17-05-2019)

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Stephane Lefrancois. Tumour suppression by blocking palmitoylation. Nature Biomedical Engineering, 2019, 3 (4), pp.255-256. ⟨10.1038/s41551-019-0383-6⟩. ⟨pasteur-02133023⟩

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